Jivora Leishmania infantum IgG-antibodies™

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Whether you've recently traveled to endemic regions or are investigating your long-term wellness, understanding your immune profile is a key part of your health journey. Jivora Leishmania infantum IgG-antibodies™ is a professional-grade screening designed to detect antibodies associated with the Leishmania parasite.

What is Leishmaniasis? Leishmaniasis is a condition caused by microscopic parasites spread through the bite of infected sandflies. Because immune markers can persist, a laboratory screening is an effective way to identify if your body has been exposed to the pathogen.

Why Choose Jivora?

  • Standardized Technology: We utilize the ELISA method, a widely recognized laboratory process that scans your blood for specific IgG antibodies.

  • Targeted Detection: This screening is calibrated to detect the antibodies associated with systemic exposure to Leishmania infantum.

  • Seamless Process: Our partner laboratories use validated methodologies to provide high-resolution data regarding your immune status.

Who It’s For:

  • International Travelers: Individuals who have visited regions where sandfly-borne pathogens are common.

  • Wellness Investigators: Those working with practitioners to map out a comprehensive internal pathogen profile.


About Your Jivora Leishmania infantum IgG-antibodies™

Convenient Access to Wellness Insights

You can order your testing kit directly through Jivora Health, an authorized ArminLabs partner. Our streamlined online process respects your privacy and security, allowing you to take a proactive role in monitoring your immune health without the need for a prior office visit.

Simple, Needle-Free Collection at Home

Each kit features the FDA-cleared Tasso+ device, designed for easy and virtually painless blood collection from the upper arm. This innovative technology allows you to collect a high-quality sample without traditional needles. If you prefer, a standard clinical blood draw option is also available. Both methods are validated for sample stability and laboratory accuracy.

Informational Results for Better Conversations

Your report provides a detailed look at how your immune system reacts to specific tick-borne antigens. These findings are educational in nature and intended to help you have more informed discussions with your healthcare provider. Please note that these results are not a medical diagnosis and should not be used as a standalone basis for a treatment plan.

Medications and Testing

While most common medications do not impact the results, certain intensive therapies - such as strong immunosuppressants, chemotherapy, or interferon-gamma therapy - may affect your immune system’s natural reactivity. We recommend consulting your clinician before sample collection if you are currently undergoing these treatments.

Fast, Secure, and Supported

Once your sample is received by the laboratory, your secure digital report is typically available within 7 to 10 business days. To help you navigate your findings, Jivora Health provides access to a complimentary educational review to explain the data markers in your report.

Comprehensive Immune Screening

Traditional screenings often focus on a single strain of Borrelia. The ArminLabs approach provides a broader perspective by screening for reactivity to Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. By including persistent-form (round-body) antigens, this test offers a more comprehensive view of your immune profile, reducing the limitations found in narrower testing methods.

Understanding Your Immune Markers

  • IgM Reactivity: Typically associated with a more recent or active immune response.

  • IgG Reactivity: Generally indicates an immune memory or long-term reactivity. ArminLabs calibrates these markers to provide you and your healthcare professional with a clear map of your immune system’s history and current status.

The Science of Antigen Diversity

Borrelia bacteria are known for their ability to shift forms, including "round-body" or pleomorphic states. Because these different forms can trigger different immune responses, our testing includes specific antigens for both active and persistent forms. This multi-antigen approach ensures a more thorough assessment of immune reactivity that standard screenings might overlook.


Regulatory Status: The Tasso+ collection device is FDA-cleared. The laboratory tests provided by ArminLabs are Laboratory Developed Tests (LDTs). These tests have not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary for LDTs when performed by a CLIA-certified laboratory.

Educational Use: These results are for informational purposes only. They are not intended to diagnose, treat, cure, or prevent any disease. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

*This test was developed and its performance characteristics determined by ArminLabs. It has not been cleared or approved by the U.S. Food and Drug Administration. This test is intended for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Technical Information
key fact
Detection of specific IgG antibodies against Leishmania infantum.
material
ELISA-based test. 1 tube of serum/Z-gel is required.
further information on the test
Leishmania-specific IgG antibodies can be detected primarily in visceral leishmaniasis.
further information on the pathogen
Leishmaniae are obligate intracellular single-celled parasites. These flagellated protozoa are transmitted via the saliva of sandflies and moth flies to sheep, dogs, and humans. They are found worldwide in the Mediterranean region, and in tropical and subtropical regions.

Three forms of leishmaniasis exist:

Visceral (internal) leishmaniasis: Caused by Leishmania donovani (in India) and Leishmania infantum (in Europe).

Cutaneous leishmaniasis: Caused by L. tropica major, L. tropica minor, L. tropica infantum, and L. aethiopica.

Mucocutaneous leishmaniasis: Caused by Leishmania brasiliensis.

Transmission: Bite of an infected sandfly or moth fly. Incubation period: Cutaneous: 2–4 weeks; Visceral: 1–6 months (sometimes over 2 years).



Symptoms:

Cutaneous leishmaniasis: Papule formation, developing into a nodule that ulcerates and heals with characteristic scarring. Predominantly affects head, neck, or arms. Usually heals spontaneously.

Visceral leishmaniasis: Remitting fever, hepatosplenomegaly (enlargement of liver and spleen), severe anemia, leukopenia, and thrombocytopenia with mucosal bleeding.

Mucocutaneous leishmaniasis: Invasive and destructive spread into the mucous membranes of the mouth and nose.

Important:These test results are for informational and educational purposes only. They provide immune response markers and are not intended to diagnose, treat, cure, or prevent any disease. This test should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before making any health-related decisions based on test results.